rabbit anti prongf antibody Search Results


polyclonal anti-prongf antibody  (Merck KGaA)
90
Merck KGaA polyclonal anti-prongf antibody
A–D. Immunohistochemical detection of <t>proNGF</t> was performed with a <t>polyclonal</t> antibody on a series of thyroid cancers (n=40), adenoma (n=40) and normal thyroid tissues (n=80). ProNGF was found in epithelial cells with a marked increased in cancer tissues. Representative pictures are shown for normal thyroid tissue (A), adenoma (B), papillary carcinoma (C), follicular carcinoma (D). Scale = 50μm. E. Quantification of proNGF staining intensities was performed using the Halo™ image analysis platform, h-scores were calculated and used to establish the ROC curves. ProNGF staining intensities were significantly higher for cancers (median h-score = 69.3) than adenomas (median h-score = 35.5) and normal tissues (median h-score = 19.7) (p<0.0001). The box limits indicate the 25th and 75th percentiles with the whiskers extending 1.5 times the interquartile range from the 25th and 75th percentiles (outliers are represented by dots) (****p<0.0001). F–H. ROC curves for proNGF staining intensity levels in thyroid cancers versus adenomas and normal thyroid tissues were established and analyzed using GraphPad™. The area under the curve was 0.99 (95% CI 0.98-1.00, p<0.0001) for cancers versus normal samples (F), 0.84 (95% CI 0.75-0.93, p<0.0001) for cancers versus adenomas (G), and 0.95 (95% CI 0.85-0.96, p<0.0001) for cancers versus adenomas and normal samples (H).
Polyclonal Anti Prongf Antibody, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+anti+prongf+antibody/anti+rabbit+polycloncal+prongf+antibody+ab9040/pmc05053740-171-1-4
Average 90 stars, based on 1 article reviews
polyclonal anti-prongf antibody - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


A–D. Immunohistochemical detection of proNGF was performed with a polyclonal antibody on a series of thyroid cancers (n=40), adenoma (n=40) and normal thyroid tissues (n=80). ProNGF was found in epithelial cells with a marked increased in cancer tissues. Representative pictures are shown for normal thyroid tissue (A), adenoma (B), papillary carcinoma (C), follicular carcinoma (D). Scale = 50μm. E. Quantification of proNGF staining intensities was performed using the Halo™ image analysis platform, h-scores were calculated and used to establish the ROC curves. ProNGF staining intensities were significantly higher for cancers (median h-score = 69.3) than adenomas (median h-score = 35.5) and normal tissues (median h-score = 19.7) (p<0.0001). The box limits indicate the 25th and 75th percentiles with the whiskers extending 1.5 times the interquartile range from the 25th and 75th percentiles (outliers are represented by dots) (****p<0.0001). F–H. ROC curves for proNGF staining intensity levels in thyroid cancers versus adenomas and normal thyroid tissues were established and analyzed using GraphPad™. The area under the curve was 0.99 (95% CI 0.98-1.00, p<0.0001) for cancers versus normal samples (F), 0.84 (95% CI 0.75-0.93, p<0.0001) for cancers versus adenomas (G), and 0.95 (95% CI 0.85-0.96, p<0.0001) for cancers versus adenomas and normal samples (H).

Journal: Oncotarget

Article Title: ProNGF is a potential diagnostic biomarker for thyroid cancer

doi: 10.18632/oncotarget.8652

Figure Lengend Snippet: A–D. Immunohistochemical detection of proNGF was performed with a polyclonal antibody on a series of thyroid cancers (n=40), adenoma (n=40) and normal thyroid tissues (n=80). ProNGF was found in epithelial cells with a marked increased in cancer tissues. Representative pictures are shown for normal thyroid tissue (A), adenoma (B), papillary carcinoma (C), follicular carcinoma (D). Scale = 50μm. E. Quantification of proNGF staining intensities was performed using the Halo™ image analysis platform, h-scores were calculated and used to establish the ROC curves. ProNGF staining intensities were significantly higher for cancers (median h-score = 69.3) than adenomas (median h-score = 35.5) and normal tissues (median h-score = 19.7) (p<0.0001). The box limits indicate the 25th and 75th percentiles with the whiskers extending 1.5 times the interquartile range from the 25th and 75th percentiles (outliers are represented by dots) (****p<0.0001). F–H. ROC curves for proNGF staining intensity levels in thyroid cancers versus adenomas and normal thyroid tissues were established and analyzed using GraphPad™. The area under the curve was 0.99 (95% CI 0.98-1.00, p<0.0001) for cancers versus normal samples (F), 0.84 (95% CI 0.75-0.93, p<0.0001) for cancers versus adenomas (G), and 0.95 (95% CI 0.85-0.96, p<0.0001) for cancers versus adenomas and normal samples (H).

Article Snippet: A polyclonal anti-proNGF antibody (Merck Millipore, Darmstadt, Germany, catalogue number AB9040) was used at 1/200 for cohort 1, and a monoclonal anti-proNGF antibody made against the proNGF propeptide sequence (in house from Biomerieux, Marcy l'Etoile, France) was used at 2.5 μg/ml for cohort 2.

Techniques: Immunohistochemical staining, Staining

ProNGF expression in thyroid cancers versus adenomas and normal tissues (cohort 1) and associations with clinicopathological parameters

Journal: Oncotarget

Article Title: ProNGF is a potential diagnostic biomarker for thyroid cancer

doi: 10.18632/oncotarget.8652

Figure Lengend Snippet: ProNGF expression in thyroid cancers versus adenomas and normal tissues (cohort 1) and associations with clinicopathological parameters

Article Snippet: A polyclonal anti-proNGF antibody (Merck Millipore, Darmstadt, Germany, catalogue number AB9040) was used at 1/200 for cohort 1, and a monoclonal anti-proNGF antibody made against the proNGF propeptide sequence (in house from Biomerieux, Marcy l'Etoile, France) was used at 2.5 μg/ml for cohort 2.

Techniques: Expressing

A-F. Immunohistochemical detection of proNGF in thyroid cancers of various histological types (n=127 cases), adenomas (n=6) and normal thyroid tissues (n=55) was performed witha monoclonal antibody. ProNGF was found in epithelial cells with a marked increased in cancer tissues. Representative pictures are shown for normal thyroid tissue (A), adenoma (B), papillary carcinoma (C), follicular carcinoma (D), medullary carcinoma (E), and anaplastic carcinoma (F). Scale = 50μm. G. Quantification of proNGF staining intensities was performed using the Halo™ image analysis platform, h-scores were calculated and used to establish the ROC curves. ProNGF staining intensities were significantly higher for cancers (median h-score = 54.6) than adenomas (median h-score = 21.7) and normal tissues (median h-score = 7.2). The box limits indicate the 25th and 75th percentiles with the whiskers extending 1.5 times the interquartile range from the 25th and 75th percentiles (outliers are represented by dots) (****p<0.0001). H. The ROC curve for proNGF staining intensity levels in thyroid cancers versus normal thyroid tissues was established and analyzed using GraphPad™. The area under the ROC curve was 0.98 (95% CI 0.97-0.99, p<0.0001).

Journal: Oncotarget

Article Title: ProNGF is a potential diagnostic biomarker for thyroid cancer

doi: 10.18632/oncotarget.8652

Figure Lengend Snippet: A-F. Immunohistochemical detection of proNGF in thyroid cancers of various histological types (n=127 cases), adenomas (n=6) and normal thyroid tissues (n=55) was performed witha monoclonal antibody. ProNGF was found in epithelial cells with a marked increased in cancer tissues. Representative pictures are shown for normal thyroid tissue (A), adenoma (B), papillary carcinoma (C), follicular carcinoma (D), medullary carcinoma (E), and anaplastic carcinoma (F). Scale = 50μm. G. Quantification of proNGF staining intensities was performed using the Halo™ image analysis platform, h-scores were calculated and used to establish the ROC curves. ProNGF staining intensities were significantly higher for cancers (median h-score = 54.6) than adenomas (median h-score = 21.7) and normal tissues (median h-score = 7.2). The box limits indicate the 25th and 75th percentiles with the whiskers extending 1.5 times the interquartile range from the 25th and 75th percentiles (outliers are represented by dots) (****p<0.0001). H. The ROC curve for proNGF staining intensity levels in thyroid cancers versus normal thyroid tissues was established and analyzed using GraphPad™. The area under the ROC curve was 0.98 (95% CI 0.97-0.99, p<0.0001).

Article Snippet: A polyclonal anti-proNGF antibody (Merck Millipore, Darmstadt, Germany, catalogue number AB9040) was used at 1/200 for cohort 1, and a monoclonal anti-proNGF antibody made against the proNGF propeptide sequence (in house from Biomerieux, Marcy l'Etoile, France) was used at 2.5 μg/ml for cohort 2.

Techniques: Immunohistochemical staining, Staining

ProNGF expression in thyroid cancers of different histological types (cohort 2) and associations with clinicopathological parameters

Journal: Oncotarget

Article Title: ProNGF is a potential diagnostic biomarker for thyroid cancer

doi: 10.18632/oncotarget.8652

Figure Lengend Snippet: ProNGF expression in thyroid cancers of different histological types (cohort 2) and associations with clinicopathological parameters

Article Snippet: A polyclonal anti-proNGF antibody (Merck Millipore, Darmstadt, Germany, catalogue number AB9040) was used at 1/200 for cohort 1, and a monoclonal anti-proNGF antibody made against the proNGF propeptide sequence (in house from Biomerieux, Marcy l'Etoile, France) was used at 2.5 μg/ml for cohort 2.

Techniques: Expressing